ARTIFICIAL INTELLIGENCE-ASSISTED SCREENING FOR NON-COMMUNICABLE DISEASE RISK IN COMMUNITY-BASED PRIMARY HEALTHCARE
DOI:
https://doi.org/10.55681/aohj.v3i1.559Keywords:
ARTIFICIAL INTELLIGENCE, PRIMARY HEALTHCARE, ARTIFICIAL INTELLIGENCE-ASSISTED SCREENINGAbstract
Non-communicable diseases remain a major challenge for primary healthcare because hypertension, diabetes, cardiovascular disease, and chronic kidney disease frequently develop silently before clinical diagnosis. This study evaluated an artificial intelligence-assisted screening framework designed to identify adults at elevated non-communicable disease risk during community-based primary healthcare encounters. A quantitative diagnostic-prediction study was designed using a simulated dataset representing 1,200 adults attending community screening services. Demographic characteristics, blood pressure, body mass index, smoking status, physical activity, family history, random blood glucose, and selected routine clinical variables were used to compare logistic regression, random forest, and gradient boosting models. Model performance was assessed through discrimination, sensitivity, specificity, F1 score, calibration, and decision-oriented risk stratification. Gradient boosting produced the strongest overall discrimination, with an area under the receiver operating characteristic curve of 0.89, sensitivity of 0.84, and specificity of 0.81 for identifying participants classified as high risk. Age, systolic blood pressure, body mass index, glucose level, smoking, and family history contributed most strongly to predictions. AI-assisted screening also increased the proportion of high-risk individuals prioritized for confirmatory assessment compared with rule-based screening alone. The findings indicate that transparent artificial intelligence can strengthen early risk recognition in community primary care when it complements, rather than replaces, professional judgment. The proposed framework contributes a practical model for targeted prevention, referral prioritization, and more efficient use of limited primary healthcare resources while emphasizing local validation, fairness, explainability, privacy, and continuous performance monitoring. This.
Downloads
References
Abdulazeem, H., Whitelaw, S., Schauberger, G., & Klug, S. J. (2023). A systematic review of clinical health conditions predicted by machine learning diagnostic and prognostic models trained or validated using real-world primary health care data. PLOS ONE, 18(9), e0274276. https://doi.org/10.1371/journal.pone.0274276
Al-Dekah, A. M., & Sweileh, W. (2025). Role of artificial intelligence in early identification and risk evaluation of non-communicable diseases: A bibliometric analysis of global research trends. BMJ Open, 15(5), e101169. https://doi.org/10.1136/bmjopen-2025-101169
Chowdhury, M. Z. I., Naeem, I., Quan, H., Leung, A. A., Sikdar, K. C., O’Beirne, M., & Turin, T. C. (2022). Prediction of hypertension using traditional regression and machine learning models: A systematic review and meta-analysis. PLOS ONE, 17(4), e0266334. https://doi.org/10.1371/journal.pone.0266334
Collins, G. S., et al. (2024). TRIPOD+AI statement: Updated guidance for reporting clinical prediction models that use regression or machine learning methods. BMJ, 385, e078378. https://doi.org/10.1136/bmj-2023-078378
Dziopa, K., Asselbergs, F. W., Gratton, J., Chaturvedi, N., & Schmidt, A. F. (2022). Cardiovascular risk prediction in type 2 diabetes: A comparison of 22 risk scores in primary care settings. Diabetologia, 65, 644–656. https://doi.org/10.1007/s00125-021-05640-y
El Sherbini, A., Rosenson, R. S., Al Rifai, M., Virk, H. U. H., Wang, Z., Virani, S., Glicksberg, B. S., Lavie, C. J., & Krittanawong, C. (2024). Artificial intelligence in preventive cardiology. Progress in Cardiovascular Diseases, 84, 76–89. https://doi.org/10.1016/j.pcad.2024.03.002
Islam, S. M. S., Talukder, A., Awal, M. A., Siddiqui, M. M. U., Ahamad, M. M., Ahammed, B., Rawal, L. B., Alizadehsani, R., Abawajy, J., Laranjo, L., Chow, C. K., & Maddison, R. (2022). Machine learning approaches for predicting hypertension and its associated factors using population-level data from three South Asian countries. Frontiers in Cardiovascular Medicine, 9, 839379. https://doi.org/10.3389/fcvm.2022.839379
Ji, W., Zhang, Y., Cheng, Y., Wang, Y., & Zhou, Y. (2022). Development and validation of prediction models for hypertension risks: A cross-sectional study based on 4,287,407 participants. Frontiers in Cardiovascular Medicine, 9, 928948. https://doi.org/10.3389/fcvm.2022.928948
Kırboğa, K. K., & Küçüksille, E. U. (2023). Identifying cardiovascular disease risk factors in adults with explainable artificial intelligence. Anatolian Journal of Cardiology, 27(11), 657–663. https://doi.org/10.14744/AnatolJCardiol.2023.3214
Kurniawan, R., Utomo, B., Siregar, K. N., Ramli, K., Besral, Suhatril, R. J., & Pratiwi, O. A. (2023). Hypertension prediction using machine learning algorithm among Indonesian adults. IAES International Journal of Artificial Intelligence, 12(2), 776–784. https://doi.org/10.11591/ijai.v12.i2.pp776-784
Moons, K. G. M., et al. (2025). PROBAST+AI: An updated quality, risk of bias, and applicability assessment tool for prediction models using regression or artificial intelligence methods. BMJ, 388, e082505. https://doi.org/10.1136/bmj-2024-082505
Salet, N., Gökdemir, A., Preijde, J., van Heck, C. H., & Eijkenaar, F. (2024). Using machine learning to predict acute myocardial infarction and ischemic heart disease in primary care cardiovascular patients. PLOS ONE, 19, e0307099. https://doi.org/10.1371/journal.pone.0307099
Salih, A., Boscolo Galazzo, I., Gkontra, P., Lee, A. M., Lekadir, K., Raisi-Estabragh, Z., & Petersen, S. E. (2023). Explainable artificial intelligence and cardiac imaging: Toward more interpretable models. Circulation: Cardiovascular Imaging, 16(4), e014519. https://doi.org/10.1161/CIRCIMAGING.122.014519
Silva, G. F. S., Fagundes, T. P., Teixeira, B. C., & Chiavegatto Filho, A. D. P. (2022). Machine learning for hypertension prediction: A systematic review. Current Hypertension Reports, 24(11), 523–533. https://doi.org/10.1007/s11906-022-01212-6
Singh, M., et al. (2024). Artificial intelligence for cardiovascular disease risk assessment in personalised framework: A scoping review. eClinicalMedicine, 73, 102660. https://doi.org/10.1016/j.eclinm.2024.102660
Susanto, A. P., Lyell, D., Widyantoro, B., Juzar, D. A., Santoso, A., Berkovsky, S., & Magrabi, F. (2025). AI-assisted cardiovascular risk assessment by general practitioners in resource-constrained Indonesian settings using a conceptual prototype: Randomized controlled study. Journal of Medical Internet Research, 27, e73131. https://doi.org/10.2196/73131
Xi, Y., Wang, H., & Sun, N. (2022). Machine learning outperforms traditional logistic regression and offers new possibilities for cardiovascular risk prediction: A study involving 143,043 Chinese patients with hypertension. Frontiers in Cardiovascular Medicine, 9, 1025705. https://doi.org/10.3389/fcvm.2022.1025705
Zhang, Y., et al. (2023). Diabetes risk prediction model based on community follow-up data using machine learning. Preventive Medicine Reports, 35, 102358. https://doi.org/10.1016/j.pmedr.2023.102358
Notoatmodjo, S. (2018). Metodologi penelitian kesehatan. Rineka Cipta. ISBN 978-979-518-984-8.
Sugiyono. (2022). Metode penelitian kuantitatif, kualitatif, dan R&D. Alfabeta. ISBN 978-602-289-533-6.
Dahlan, M. S. (2020). Statistik untuk kedokteran dan kesehatan: Deskriptif, bivariat, dan multivariat, dilengkapi aplikasi menggunakan SPSS. Epidemiologi Indonesia. ISBN 978-602-8199-32-2.
Jalepalli, S. K., et al. (2024). Development and validation of multicentre study on novel Artificial Intelligence-based Cardiovascular Risk Score (AICVD). Family Medicine and Community Health, 12(Suppl 1), e002340. https://doi.org/10.1136/fmch-2023-002340
Krittanawong, C., et al. (2024). Use of artificial intelligence in improving outcomes in heart disease: A scientific statement from the American Heart Association. Circulation, 149(14), e1028–e1050. https://doi.org/10.1161/CIR.0000000000001201
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Kusumayadi, Rian Saprial, Marnah

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.





